Recent policy changes by the NIH and DHHS require the use of a single IRB of record for multisite research.
The Network has established three Central IRBs (CIRBs) to help meet this requirement. We will provide resources, tools, and a web-based platform () to ensure all site investigators understand how to use a CIRB at their institution, from initial submission to study closeout. The CIRBs use the SMART IRB Authorization Agreement as the basis for reliance.